5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid → HCID 86611511, compound

HRID 2108321Notes

Reaction equation

HRID 2108321 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21]([OH:23])=O)[C:9]=2[CH3:24])=[CH:4][CH:3]=1.Cl.[F:26][C:27]1([F:34])[CH2:32][CH2:31][N:30]([NH2:33])[CH2:29][CH2:28]1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21]([NH:33][N:30]3[CH2:31][CH2:32][C:27]([F:34])([F:26])[CH2:28][CH2:29]3)=[O:23])[C:9]=2[CH3:24])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 15194215-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acidHCID 68872860HCID 68872860, compound

Product 1

HCID 86611511HCID 86611511, compound

Procedure

Form the acid chloride from 3.6 mmol of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid and react it with 2.6 mmol of the product of Example 28 using the general procedure set forth in Example 39, to yield the title compound as a white solid.

Sources & evidence

ORD record
ord-4b746b76f9b94869b66e53419165a4e7
Source dataset
uspto-grants-2009_04
Patent number
US07514068B2

Reaction notes

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