5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid → HCID 86611512, compound

HRID 2108322Notes

Reaction equation

HRID 2108322 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21]([OH:23])=O)[C:9]=2[CH3:24])=[CH:4][CH:3]=1.Cl.[F:26][C:27]1([F:36])[CH2:32][C:31]([F:34])([F:33])[CH2:30][N:29]([NH2:35])[CH2:28]1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21]([NH:35][N:29]3[CH2:28][C:27]([F:26])([F:36])[CH2:32][C:31]([F:33])([F:34])[CH2:30]3)=[O:23])[C:9]=2[CH3:24])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 15194215-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acidHCID 68872210HCID 68872210, compound

Product 1

HCID 86611512HCID 86611512, compound

Procedure

Form the acid chloride from 2.0 mmol of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid and react it with 1.4 mmol of the product of Example 33 using the general procedure set forth in Example 39, to yield the title compound as a white solid.

Sources & evidence

ORD record
ord-aa651554fc79487ea13c4e304829534e
Source dataset
uspto-grants-2009_04
Patent number
US07514068B2

Reaction notes

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