HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1H-imidazole-4-carbonitrile → HCID 67213626, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1H-imidazole-4-carbonitrile | HCID 78777 | — |
| Reactant | 4,4,4-Trifluoro-1-(4-methylphenyl)butane-1,3-dione | HCID 550193 | — |
| Product | HCID 67213626 | HCID 67213626 | 44% |
Reaction Steps
Reaction of 1-(4-methyl-phenyl)-4,4,4-trifluoro-butane-1,3-dione (230 mg, 1.0 mmol), prepared from commercially available 4-methyl-acetophenone according to general procedure A, and 4-amino-5-cyano-1H-imidazole (108 mg, 1.0 mmol) according to general procedure B yielded the title compound as a yellow solid (133 mg, 44%). MS (ISP) 303.1 [(M+H)+]; mp 197° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514443B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-2cd14269e3eb4efd8c2f702d18d1c780 |
| Source note | uspto-grants-2009_04 |