HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1H-imidazole-4-carbonitrile → HCID 67213184, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1H-imidazole-4-carbonitrile | HCID 78777 | — |
| Reactant | 2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)- | HCID 139903 | — |
| Product | HCID 67213184 | HCID 67213184 | 39.3% |
Reaction Steps
Reaction of 1-(4-methoxy-phenyl)-4,4,4-trifluoro-butane-1,3-dione (246 mg, 1.0 mmol), prepared from commercially available 4-methoxy-acetophenone according to general procedure A, and 4-amino-5-cyano-1H-imidazole (108 mg, 1.0 mmol) according to general procedure B yielded the title compound as a yellow solid (125 mg, 39%). MS (ISP) 319.1 [(M+H)+]; mp 192° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514443B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-219220c0eecc4b15bea6e3d6201fa042 |
| Source note | uspto-grants-2009_04 |