HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68565908, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Bromo-1,1-difluoroethane | HCID 136186 | — |
| Reactant | HCID 24783268 | HCID 24783268 | — |
| Reactant | HCID 68560856 | HCID 68560856 | — |
| Product | HCID 68565908 | HCID 68565908 | — |
Reaction Steps
According to the procedure described for the synthesis of [3-(1-isobutyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1-methyl-1H-indol-6-yl]-(4-isopropyl-piperazin-1-yl)-methanone; hydrochloride (example 42) the title compound was prepared from [3-(1-isobutyl-piperidin-4-yl)-1H-indol-6-yl]-(4-isopropyl-piperazin-1-yl)-methanone (example 2, free base) and 2-bromo-1,1-difluoroethane (commercially available). MS (m/e): 475.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514433B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-ab507ccf0ae04a82a4a2c779089c586c |
| Source note | uspto-grants-2009_04 |