1-Isopropylpiperazine → HCID 68563887, compound

Participants

Reaction Steps

According to the procedure described for the conversion of an ester functionality to a piperazine amide functionality like in example 72, step 2 the title compound was prepared from 3-(4-isobutyl-morpholin-2-yl)-1H-indole-6-carboxylic acid methyl ester and (after ester cleavage with LiOH.H2O), 1-(2-propyl)-piperazine (commercially available). The title compound was obtained as light brown foam. MS (m/e): 413.4 (MH+).

Provenance & Evidence