Thionyl Chloride → 5-(4-nitrophenyl)furan-2-carbonyl Chloride

HRID 2108689Notes

Reaction equation

HRID 2108689 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:14][C:13]([C:15]([OH:17])=O)=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].S(Cl)([Cl:20])=O>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:14][C:13]([C:15]([Cl:20])=[O:17])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 1615935-(4-Nitrophenyl)-2-furancarboxylic acid

Product 1

HCID 38299835-(4-nitrophenyl)furan-2-carbonyl Chloride

Procedure

Was prepared by stirring a mixture of 5-(4-nitrophenyl)-2-furoic acid (1.0 g, 4.3 mmol) and thionyl chloride (10 ml) at reflux for 2 hours. The mixture was evaporated and co-evaporated with anhydrous toluene. The acid chloride was used without further purification.

Workup

  1. customWas prepared
  2. temperatureat reflux for 2 hours
  3. customThe mixture was evaporated
  4. customThe acid chloride was used without further purification

Sources & evidence

ORD record
ord-1153b67899be4f67b82517a728ab99f0
Source dataset
uspto-grants-2009_04
Patent number
US07514450B2

Reaction notes

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