Water → 5-Bromothiophene-3-carboxylic acid

Participants

Reaction Steps

Thiophene-3-carboxylic acid (0.51 g, 4 mmol) was dissolved in HOAc (5 mL) and Br2 (0.21 mL, 4 mmol) was added in 1 mL HOAc. The reaction mixture was stirred for 40 minutes, poured into water and a white precipitate formed, which was filtered and dried to 0.70 g grams of product that contains about 30% 2,5-dibromothiophane-3-carboxylic acid.

Provenance & Evidence