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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2108757Generated: October 30, 2026

4-Bromo-2-thiophenecarboxylic Acid → N-(3-Methoxybenzyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-2-carboxamide

https://huagongshe.com/reaction/2108757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-thiophenecarboxylic AcidHCID 610409—
ReactantN-(3-Methoxybenzyl)-5-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-3-carboxamideHCID 57633062—
ProductN-(3-Methoxybenzyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-2-carboxamideHCID 57633192—

Reaction Steps

The above compound was made by the same procedure as N-(3-methoxybenzyl)-5-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-3-carboxamide starting with the regioisomer, 4-bromothiophene-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514448B2
Source datasetuspto-grants-2009_04
ORD IDord-da59599092b64a03bd5870bf4dcd0bed
Source noteuspto-grants-2009_04