Trifluoroacetic acid → HCID 136072161, compound

Participants

Reaction Steps

Trifluoroacetic acid (1 mL) was added to a stirred solution of [2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-thiazol-4-yl]-carbamic acid tert-butyl ester (0.1 g, 0.316 mmol) in CH2Cl2 (2 mL) and stirred at room temperature for 2 h. The solution was poured into ice/water and basified with saturated NaHCO3 and extracted with EtOAc (3×25 mL). The combined organic extracts were dried and concentrated to afford title compound as a pale green solid (0.058 g, 85%); Mass Spec.; MS 217 (M+1)

Provenance & Evidence