Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Hydroxy-2-{[(oxan-2-yl)oxy]methyl}-4H-pyran-4-one | HCID 13711789 | — |
| Product | HCID 12148990 | HCID 12148990 | 71% |
Reaction Steps
The compound was prepared according to example 11 using 5-hydroxy-2-(tetrahydro-pyran-2-yloxymethyl)-4H-pyran-4-one (1.00 g, 4.42 mmol), Cs2CO3 (1.58 g, 4.86 mmol) and 1,4-dibromobutane (2.00 mL, 16.7 mmol). The sealed tube was heated at 80° C. for 2 h 30. A white solid 2 was obtained (1.14 g, 71% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07514432B2 |
|---|
| Source dataset | uspto-grants-2009_04 |
|---|
| ORD ID | ord-48419d700b3c4de6a9b77a70a1501287 |
|---|
| Source note | uspto-grants-2009_04 |
|---|
