Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1,8-Dibromooctane | HCID 78310 | — |
| Reactant | 5-Hydroxy-2-{[(oxan-2-yl)oxy]methyl}-4H-pyran-4-one | HCID 13711789 | — |
| Product | HCID 17975812 | HCID 17975812 | 78% |
Reaction Steps
The compound was prepared according to the example 11 procedure using 5-hydroxy-2-(tetrahydro-pyran-2-yloxymethyl)-4H-pyran-4-one (1.00 g, 4.42 mmol), Cs2CO3 (1.58 g, 4.86 mmol) and 1,8-dibromooctane (4.12 mL, 22.1 mmol). The sealed tube was heated at 80° C. for 2 h 30. A white solid 5 was obtained (1.40 g, 78% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07514432B2 |
|---|
| Source dataset | uspto-grants-2009_04 |
|---|
| ORD ID | ord-ce57f70313d347f684c27bc72754cb3f |
|---|
| Source note | uspto-grants-2009_04 |
|---|
