Methanol → 2-(4-Bromo-phenyl)-3-(1-methyl-piperidin-4-yl)-propionic acid methyl ester

HRID 210886Notes

Reaction equation

HRID 210886 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[OH:11])[CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([CH3:19])[CH2:17][CH2:18]2)[cH:6][cH:7]1.[CH3:20][OH:21].[S:22]([Cl:23])([Cl:24])=[O:25]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9]([O:10][CH3:20])=[O:11])[CH2:12][CH:13]2[CH2:14][CH2:15][N:16]([CH3:19])[CH2:17][CH2:18]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 592383282-(4-Bromo-phenyl)-3-(1-methyl-piperidin-4-yl)-propionic acid

Product 1

HCID 592382632-(4-Bromo-phenyl)-3-(1-methyl-piperidin-4-yl)-propionic acid methyl ester

Sources & evidence

ORD record
ord-9e35cc8542784827bc50b8ebf066b9b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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