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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2108886Generated: October 31, 2026

3-(4-Methyl-1-piperazine)propan-1-ol → 4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazoline

https://huagongshe.com/reaction/2108886

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1-piperazine)propan-1-olHCID 79208—
Reactant4-Chloro-6-methoxyquinazolin-7-olHCID 135742251—
Product4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazolineHCID 11245061—

Reaction Steps

The compound was synthesised according to GP 4 from 4-chloro-7-hydroxy-6-methoxy-quinazoline and 3-(4-methylpiperazin-1-yl)-propan-1-ol. LC/ESI-MS: m/z=351 [M+H].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514460B2
Source datasetuspto-grants-2009_04
ORD IDord-930b34d3ae9b42e9891a29744afc86af
Source noteuspto-grants-2009_04