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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2108887Generated: October 31, 2026

3-(4-Methyl-1-piperazine)propan-1-ol → 4-Chloro-7-methoxy-6-(3-(4-methylpiperazin-1-yl)propoxy)quinazoline

https://huagongshe.com/reaction/2108887

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1-piperazine)propan-1-olHCID 79208—
Reactant4-Chloro-7-methoxyquinazolin-6-olHCID 23132475—
Product4-Chloro-7-methoxy-6-(3-(4-methylpiperazin-1-yl)propoxy)quinazolineHCID 23132474—

Reaction Steps

The compound was synthesised according to GP 4 from 4-chloro-6-hydroxy-7-methoxy-quinazoline and 3-(4-methylpiperazin-1-yl)-propan-1-ol. LC/ESI-MS: m/z=351 [M+H].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514460B2
Source datasetuspto-grants-2009_04
ORD IDord-004ce24f7d3a4bf7b55a07af64221b91
Source noteuspto-grants-2009_04