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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2108889Generated: October 25, 2026

1-Pyrrolidinepropanol → 4-Chloro-7-methoxy-6-(3-pyrrolidin-1-yl-propoxy)-quinazoline

https://huagongshe.com/reaction/2108889

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PyrrolidinepropanolHCID 209342—
Reactant4-Chloro-7-methoxyquinazolin-6-olHCID 23132475—
Product4-Chloro-7-methoxy-6-(3-pyrrolidin-1-yl-propoxy)-quinazolineHCID 86238565—

Reaction Steps

The compound was synthesised according to GP 4 from 4-chloro-6-hydroxy-7-methoxy-quinazoline and 3-Pyrrolidin-1-yl-propan-1-ol. LC/ESI-MS: m/z=322 [M+H].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514460B2
Source datasetuspto-grants-2009_04
ORD IDord-55e5754284754b2683eba01f0c009902
Source noteuspto-grants-2009_04