1-(2-Hydroxyethyl)-4-methylpiperazine → HCID 86248037, compound

HRID 2108892Notes

Reaction equation

HRID 2108892 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:13][CH3:14])=[C:9]([OH:12])[CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH3:15][N:16]1[CH2:21][CH2:20][N:19]([CH2:22][CH2:23]O)[CH2:18][CH2:17]1>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:13][CH3:14])=[C:9]([O:12][CH2:23][CH2:22][N:19]3[CH2:20][CH2:21][N:16]([CH3:15])[CH2:17][CH2:18]3)[CH:10]=2)[N:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 2311841-(2-Hydroxyethyl)-4-methylpiperazineHCID 231324754-Chloro-7-methoxyquinazolin-6-ol

Product 1

HCID 86248037HCID 86248037, compound

Procedure

The compound was synthesised according to GP 4 from 4-chloro-6-hydroxy-7-methoxy-quinazoline and 2-(4-Methyl-piperazin-1-yl)-ethanol. LC/ESI-MS: m/z=337 [M+H].

Workup

  1. customThe compound was synthesised

Sources & evidence

ORD record
ord-59083f898f344684bd0d681cb02c8995
Source dataset
uspto-grants-2009_04
Patent number
US07514460B2

Reaction notes

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