Benzoyl chloride → HCID 11626698, compound

HRID 2108904Notes

Reaction equation

HRID 2108904 reaction equation
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][C:21]=1[O:22][CH3:23])[N:18]=[CH:17][N:16]=[C:15]2[NH:24][C:25]1[S:26][C:27]2[CH:33]=[C:32]([NH2:34])[CH:31]=[CH:30][C:28]=2[N:29]=1>>[CH3:10][O:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][C:21]=1[O:22][CH3:23])[N:18]=[CH:17][N:16]=[C:15]2[NH:24][C:25]1[S:26][C:27]2[CH:33]=[C:32]([NH:34][C:1](=[O:8])[C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[CH:31]=[CH:30][C:28]=2[N:29]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 86248039N2-(6,7-dimethoxyquinazolin-4-yl)benzothiazole-2,6-diamine

Product 1

HCID 11626698HCID 11626698, compound

Procedure

N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl ]benzamide was prepared from benzoyl chloride (14 μL, 0.113 mmol) and N2-(6,7-dimethoxyquinazolin-4-yl)benzothiazole-2,6-diamine (40 mg, 0.113 mmol) according to GP 2 (yellowish solid, 40 mg, 87 mmol, 77%). LC/ESI-MS: m/z=458 [M+H]+; m/z=456 [M−H]−; Rt=3.13 min.

Sources & evidence

ORD record
ord-8e87205aaa8a45aab5a0ab708610b9fb
Source dataset
uspto-grants-2009_04
Patent number
US07514460B2

Reaction notes

Loading…