HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzoyl Chloride → N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl]-4-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzoyl Chloride | HCID 13405 | — |
| Reactant | N2-(6,7-dimethoxyquinazolin-4-yl)benzothiazole-2,6-diamine | HCID 86248039 | — |
| Product | N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl]-4-methylbenzamide | HCID 11641366 | — |
Reaction Steps
N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl]-4-methylbenzamide was prepared from p-toluoyl chloride (17.5 mg, 0.113 mmol) and N2-(6,7-dimethoxyquinazolin-4-yl)benzothiazole-2,6-diamine (40 mg, 0.113 mmol) according to GP 2 (yellowish solid, 44 mg, 93 μmol, 82%). LC/ESI-MS: m/z=472 [M+H]+; m/z=470 [M−H]−; R′, =3.32 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514460B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-c7738b7dbc1f4bc49e9a8cdbf5f2d0f7 |
| Source note | uspto-grants-2009_04 |