5,5-Dimethyloxazolin-2-one → 3-{3,5-Difluoro-4-[4-(5-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-5,5-dimethyloxazolidin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:24])[c:5]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]([F:8])[cH:7]1.[CH3:25][C:26]1([CH3:32])[CH:27]=[N:28][C:29](=[O:31])[O:30]1>>[c:2]1([N:28]2[CH2:27][C:26]([CH3:25])([CH3:32])[O:30][C:29]2=[O:31])[cH:3][c:4]([F:24])[c:5]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-c7928745dddd4b59993463b4fc2e84ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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