HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzoyl chloride → N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl]-4-trifluoromethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzoyl chloride | HCID 67607 | — |
| Reactant | N2-(6,7-dimethoxyquinazolin-4-yl)benzothiazole-2,6-diamine | HCID 86248039 | — |
| Product | N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl]-4-trifluoromethylbenzamide | HCID 11635049 | — |
Reaction Steps
N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl]-4-trifluoromethylbenzamide was prepared from p-trifluoromethylbenzoyl chloride (17 μL, 0.113 mmol) and N2-(6,7-dimethoxyquinazolin-4-yl)benzothiazole-2,6-diamine (40 mg, 0.113 mmol) according to GP 2 (yellowish solid, 44 mg, 83 μmol, 73%). LC/ESI-MS: m/z=526 [M+H]+; m/z=524 [M−H]−; Rt=3.67 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514460B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-62e353891d874a05a9d03ee9c2a6a7de |
| Source note | uspto-grants-2009_04 |