Diethyl Ether → Methyl 6-(3-acetylamino-1-pyrrolidinyl)-2-(2,4-difluorophenylamino)-5-fluoronicotinate
Reaction equation
[CH3:27][C:28](=[O:29])[O:30][C:31](=[O:32])[CH3:33].[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[CH:39]([Cl:40])([Cl:41])[Cl:42].[NH2:1][CH:2]1[CH2:3][N:4]([c:7]2[n:8][c:9]([NH:18][c:19]3[c:20]([F:26])[cH:21][c:22]([F:25])[cH:23][cH:24]3)[c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][c:16]2[F:17])[CH2:5][CH2:6]1>>[NH:1]([CH:2]1[CH2:3][N:4]([c:7]2[n:8][c:9]([NH:18][c:19]3[c:20]([F:26])[cH:21][c:22]([F:25])[cH:23][cH:24]3)[c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][c:16]2[F:17])[CH2:5][CH2:6]1)[C:28]([CH3:27])=[O:29]Participants
5
Sources & evidence
- ORD record
- ord-f4580047020c49239e480c417a544fcb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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