HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178473965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Iodobenzoic acid | HCID 12060 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 1-Acetyl-6-chloro-1,3-dihydro-2H-indol-2-one | HCID 11644161 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178473965 | HCID 178473965 | — |
Reaction Steps
10.5 g 1-acetyl-6-chloro-2-indolinone (educt V.1), 13.6 g 3-iodobenzoic acid and 17.7 g TBTU are placed in 100 ml of dimethylformamide, 35 ml triethylamine are added and the mixture is stirred for 12 hours at ambient temperature. After this time the solvent is eliminated, the residue is combined with water, suction filtered and washed with a little water, methanol and ether and dried in vacuo at 100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514468B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-876d780ab8234cd5a96eb486e27c6a74 |
| Source note | uspto-grants-2009_04 |