Benzene, (triethoxymethyl)- → HCID 69061213, compound

HRID 2109018Notes

Reaction equation

HRID 2109018 reaction equation
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([Cl:13])[CH:11]=2)[CH2:6][C:5]1=[O:14])(=[O:3])[CH3:2].[CH3:15][CH2:16][O:17][C:18](OCC)(OCC)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C(OC(=O)C)(=O)C>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([Cl:13])[CH:11]=2)[C:6](=[C:18]([O:17][CH2:16][CH3:15])[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:5]1=[O:14])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 74268Benzene, (triethoxymethyl)-HCID 116441611-Acetyl-6-chloro-1,3-dihydro-2H-indol-2-one

Product 1

HCID 69061213HCID 69061213, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

A solution of 41.9 g 1-acetyl-6-chloro-2-indolinone (educt V.1) and 136 ml triethyl orthobenzoate in 150 ml acetic anhydride is stirred for six hours at 120° C. After cooling the mixture is evaporated down by half, the crystals precipitated are suction filtered and dried at 100° C. in vacuo.

Workup

  1. temperatureAfter cooling the mixture
  2. customis evaporated down by half
  3. customthe crystals precipitated
  4. filtrationare suction filtered
  5. customdried at 100° C. in vacuo

Sources & evidence

ORD record
ord-cdca35b94efc45e18c5e4a4ddfb528da
Source dataset
uspto-grants-2009_04
Patent number
US07514468B2

Reaction notes

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