HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N1-cyclohexyl-N2-(2,2,2-trifluoroethyl)glycinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycine | HCID 57633731 | — |
| Product | N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N1-cyclohexyl-N2-(2,2,2-trifluoroethyl)glycinamide | HCID 11774153 | — |
Reaction Steps
Synthesized as described in example 3 using N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycine and cyclohexylamine: 1H NMR (400 MHz, CDCl3) δ 7.68 (d, J=8.8 Hz, 1H), 7.03 (d, J=2.6 Hz, 1H), 6.92 (dd, J=8.8, 2.7 Hz, 1H), 5.81 (d, J=8.0 Hz, 1H), 4.12 (s, 2H), 4.10 (q, J=8.6 Hz, 2H), 3.80 (m, 1H), 1.83 (m, 2H), 1.63 (m, 3H), 1.32 (m, 2H), 1.08 (m, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514470B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-9f5e32f6e40247e2b258d9cd8bf0b647 |
| Source note | uspto-grants-2009_04 |