2-Propenoic acid, 2-(bromomethyl)-, methyl ester → HCID 57633726, compound

HRID 2109098Notes

Reaction equation

HRID 2109098 reaction equation
[F:1][C:2]([F:18])([F:17])[CH2:3][NH:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:16])([F:15])[F:14])[CH:6]=1.Br[CH2:20][C:21](=[CH2:26])[C:22]([O:24][CH3:25])=[O:23]>>[C:9]([C:8]1[CH:11]=[CH:12][C:5]([N:4]([CH2:26][C:21](=[CH2:20])[C:22]([O:24][CH3:25])=[O:23])[CH2:3][C:2]([F:17])([F:18])[F:1])=[CH:6][C:7]=1[C:13]([F:16])([F:14])[F:15])#[N:10]

Participants

3

Reactant 2

HCID 5210932-Propenoic acid, 2-(bromomethyl)-, methyl esterHCID 431385374-((2,2,2-Trifluoroethyl)amino)-2-(trifluoromethyl)benzonitrile

Product 1

HCID 57633726HCID 57633726, compound

Procedure

Synthesized as described in example 2 from 4-[(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and methyl 2-(bromomethyl)acrylate: MS (ES) m/z 367 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-3582044e469c4a29be0d918dbe9f170a
Source dataset
uspto-grants-2009_04
Patent number
US07514470B2

Reaction notes

Loading…