tert-Butyl 2-bromopropanoate → HCID 11152689, compound

HRID 2109112Notes

Reaction equation

HRID 2109112 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([NH:10][CH2:11][C:12]([F:15])([F:14])[F:13])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].Br[CH:17]([CH3:25])[C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19]>>[Cl:1][C:2]1[CH:9]=[C:8]([N:10]([CH2:11][C:12]([F:13])([F:14])[F:15])[C@H:17]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH3:25])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 545327tert-Butyl 2-bromopropanoateHCID 43348132HCID 43348132, compound

Product 1

HCID 11152689HCID 11152689, compound

Procedure

Synthesized in a manner similar to example 1B using 2-chloro-4-[(2,2,2-trifluoroethyl)amino]benzonitrile and 1,1-dimethylethyl 2-bromopropanoate: MS (ES) m/z 363 (M+1).

Workup

  1. customSynthesized in a manner similar to example 1B

Sources & evidence

ORD record
ord-353d54318f7746e4abdef915e4716620
Source dataset
uspto-grants-2009_04
Patent number
US07514470B2

Reaction notes

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