tert-Butyl 2-bromobutanoate → HCID 11485715, compound

HRID 2109114Notes

Reaction equation

HRID 2109114 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([NH:10][CH2:11][C:12]([F:15])([F:14])[F:13])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].Br[CH:17]([CH2:25][CH3:26])[C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19]>>[Cl:1][C:2]1[CH:9]=[C:8]([N:10]([CH2:11][C:12]([F:13])([F:14])[F:15])[CH:17]([CH2:25][CH3:26])[C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 13124118tert-Butyl 2-bromobutanoateHCID 43348132HCID 43348132, compound

Product 1

HCID 11485715HCID 11485715, compound

Procedure

Synthesized in a manner similar to example 1B using 2-chloro-4-[(2,2,2-trifluoroethyl)amino]benzonitrile and tert-butyl 2-bromobutanoate: MS (ES) m/z 377 (M+1).

Workup

  1. customSynthesized in a manner similar to example 1B

Sources & evidence

ORD record
ord-4077f549e9a640cfb29e9aa2e20b4f6c
Source dataset
uspto-grants-2009_04
Patent number
US07514470B2

Reaction notes

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