tert-Butyl 2-bromobutanoate → HCID 57633718, compound

HRID 2109119Notes

Reaction equation

HRID 2109119 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([NH:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].Br[CH:16]([CH2:24][CH3:25])[C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18]>>[Cl:1][C:2]1[CH:9]=[C:8]([N:10]([CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH:16]([CH2:24][CH3:25])[C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 13124118tert-Butyl 2-bromobutanoateHCID 43560354HCID 43560354, compound

Product 1

HCID 57633718HCID 57633718, compound

Procedure

Synthesized in a manner similar to example 1B using 2-chloro-4-[(cyclopropylmethyl)amino]benzonitrile and tert-butyl 2-bromobutanoate: MS (ES) m/z 349 (M+1).

Workup

  1. customSynthesized in a manner similar to example 1B

Sources & evidence

ORD record
ord-fdf393ff2548469e9ed094fef776f65c
Source dataset
uspto-grants-2009_04
Patent number
US07514470B2

Reaction notes

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