tert-Butyl 2-bromopropanoate → HCID 67011150, compound

HRID 2109123Notes

Reaction equation

HRID 2109123 reaction equation
[F:1][C:2]([F:16])([F:15])[CH2:3][NH:4][C:5]1[CH:6]=[C:7]([C:13]#[N:14])[C:8]([C:11]#[N:12])=[CH:9][CH:10]=1.Br[CH:18]([CH3:26])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20]>>[C:13]([C:7]1[CH:6]=[C:5]([N:4]([CH2:3][C:2]([F:15])([F:16])[F:1])[C@H:18]([C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH3:26])[CH:10]=[CH:9][C:8]=1[C:11]#[N:12])#[N:14]

Participants

3

Reactant 2

HCID 545327tert-Butyl 2-bromopropanoateHCID 576337284-[(2,2,2-Trifluoroethyl)amino]-1,2-benzenedicarbonitrile

Product 1

HCID 67011150HCID 67011150, compound

Procedure

Synthesized in a manner similar to example 1B using 4-[(2,2,2-trifluoroethyl)amino]-1,2-benzenedicarbonitrile and 1,1-dimethylethyl 2-bromopropanoate: MS (ES) m/z 354 (M+1).

Workup

  1. customSynthesized in a manner similar to example 1B

Sources & evidence

ORD record
ord-c2115baab8794502b962b33e46f7acdd
Source dataset
uspto-grants-2009_04
Patent number
US07514470B2

Reaction notes

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