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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109151Generated: October 25, 2026

Ethynylpyridine → 4-Methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzoic acid

https://huagongshe.com/reaction/2109151

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthynylpyridineHCID 137268—
Reactant3-Azido-4-methylbenzoic acidHCID 17973091—
Reactant3-[4-(6-Chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acidHCID 21097292—
Product4-Methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzoic acidHCID 21097330—

Reaction Steps

4-Methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzoic acid was prepared from 3-azido-4-methyl benzoic acid and 2-ethynyl pyridine (Aldrich) in the same manner as 3-[4-(6-chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acid (Example 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-f0dccad609834a8598f114c4da25e2db
Source noteuspto-grants-2009_04