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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109152Generated: October 25, 2026

N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide → N-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzamide

https://huagongshe.com/reaction/2109152

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamideHCID 10214710—
Reactant4-Methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzoic acidHCID 21097330—
ProductN-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzamideHCID 21097216—

Reaction Steps

Example 3 was prepared by coupling 4-methyl-3-(4-pyridin-2-yl-[1,2,3]triazol-1-yl)-benzoic acid with N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methane-sulfonamide in the same manner as Example 1. ESI MS m/z 533 [C27H30N6O4S+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-86f695dc912643d68617aeb43c1a514a
Source noteuspto-grants-2009_04