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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109160Generated: October 26, 2026

N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide → N-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3,4-dimethyl-5-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzamide

https://huagongshe.com/reaction/2109160

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamideHCID 10214710—
Reactant3,4-Dimethyl-5-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acidHCID 21097296—
ProductN-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3,4-dimethyl-5-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzamideHCID 21097178—

Reaction Steps

Example 8 was prepared by coupling 3,4-dimethyl-5-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid with N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methane-sulfonamide in the same manner as Example 1. ESI MS m/z 549 [C28H32N6O4S+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-6ef6a06a84224160b1f566c24d48e162
Source noteuspto-grants-2009_04