HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethynyl-2-methylpyridine → 4-Methyl-3-[4-(2-methyl-pyridin-3-yl)-[1,2,3]triazol-1-yl]-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethynyl-2-methylpyridine | HCID 14526587 | — |
| Reactant | 3-Azido-4-methylbenzoic acid | HCID 17973091 | — |
| Reactant | 3,4-Dimethyl-5-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid | HCID 21097296 | — |
| Product | 4-Methyl-3-[4-(2-methyl-pyridin-3-yl)-[1,2,3]triazol-1-yl]-benzoic acid | HCID 21097325 | — |
Reaction Steps
4-Methyl-3-[4-(2-methyl-pyridin-3-yl)-[1,2,3]triazol-1-yl]-benzoic acid (5:3 mixture with 4-methyl-3-[5-(2-methyl-pyridin-3-yl)-[1,2,3]triazol-1-yl]-benzoic acid) was prepared from 3-azido-4-methyl benzoic acid and 2-methyl-3-ethynyl pyridine in the same manner as 3,4-dimethyl-5-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid (Example 8).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514458B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-d54ddb258de64aca8a2a59e131dd5a54 |
| Source note | uspto-grants-2009_04 |