3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide → HCID 21097172, compound

HRID 2109199Notes

Reaction equation

HRID 2109199 reaction equation
[N:1]([C:4]1[CH:5]=[C:6]([CH:27]=[CH:28][C:29]=1[CH3:30])[C:7]([NH:9][C:10]1[CH:15]=[C:14]([C:16]([CH3:19])([CH3:18])[CH3:17])[CH:13]=[C:12]([NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[C:11]=1[O:25][CH3:26])=[O:8])=[N+:2]=[N-:3].[CH:31]1([NH:34][C:35]2[CH:40]=[CH:39][C:38]([C:41]#[CH:42])=[CH:37][N:36]=2)[CH2:33][CH2:32]1>>[C:16]([C:14]1[CH:13]=[C:12]([NH:20][S:21]([CH3:24])(=[O:22])=[O:23])[C:11]([O:25][CH3:26])=[C:10]([NH:9][C:7](=[O:8])[C:6]2[CH:27]=[CH:28][C:29]([CH3:30])=[C:4]([N:1]3[CH:42]=[C:41]([C:38]4[CH:37]=[N:36][C:35]([NH:34][CH:31]5[CH2:33][CH2:32]5)=[CH:40][CH:39]=4)[N:3]=[N:2]3)[CH:5]=2)[CH:15]=1)([CH3:18])([CH3:19])[CH3:17]

Participants

3

Reactant 2

HCID 210792023-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamideHCID 21097355N-Cyclopropyl-5-ethynyl-2-pyridinamine

Product 1

HCID 21097172HCID 21097172, compound

Procedure

Example 26 was prepared from 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide and cyclopropyl-(5-ethynyl-pyridin-2-yl)-amine in the same manner as Example 15. ESI MS m/z 590 [C30H35N7O4S+H]+.

Sources & evidence

ORD record
ord-2835540758324cdba097c78217783a58
Source dataset
uspto-grants-2009_04
Patent number
US07514458B2

Reaction notes

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