2-Chloro-5-ethynylpyridine → HCID 21097318, compound

HRID 2109206Notes

Reaction equation

HRID 2109206 reaction equation
Br[C:2]1[N:6]([CH3:7])[C:5]([N:8]2[CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)=[N:4][CH:3]=1.Cl[C:15]1[CH:20]=CC(C#C)=CN=1>>[C:15]([C:2]1[N:6]([CH3:7])[C:5]([N:8]2[CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)=[N:4][CH:3]=1)#[CH:20]

Participants

3

Reactant 2

HCID 106542812-Chloro-5-ethynylpyridineHCID 21097317HCID 21097317, compound

Product 1

HCID 21097318HCID 21097318, compound

Procedure

4-(5-Ethynyl-1-methyl-1H-imidazol-2-yl)-morpholine was prepared from 4-(5-bromo-1-methyl-1H-imidazol-2-yl)-morpholine in the same manner as 2-chloro-5-ethynyl-pyridine (Example 1).

Sources & evidence

ORD record
ord-506ffe6f94cf4d07836b8a286012441f
Source dataset
uspto-grants-2009_04
Patent number
US07514458B2

Reaction notes

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