Isobutyramide → 1-Methyl-2-(propan-2-yl)-1H-imidazole-5-carbaldehyde

HRID 2109230Notes

Reaction equation

HRID 2109230 reaction equation
C(N)(=O)C(C)C.[CH:7]1([C:10]2[N:14]([CH3:15])[C:13]([CH:16]=[O:17])=[CH:12][N:11]=2)[CH2:9][CH2:8]1>>[CH:7]([C:10]1[N:14]([CH3:15])[C:13]([CH:16]=[O:17])=[CH:12][N:11]=1)([CH3:9])[CH3:8]

Participants

3

Reactant 2

HCID 68424IsobutyramideHCID 210972742-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde

Product 1

HCID 179567831-Methyl-2-(propan-2-yl)-1H-imidazole-5-carbaldehyde

Procedure

2-Isopropyl-3-methyl-3H-imidazole-4-carbaldehyde was prepared from isobutyramide in the same manner as 2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde (Example 46).

Sources & evidence

ORD record
ord-08118729529349d8a9c792f011e92909
Source dataset
uspto-grants-2009_04
Patent number
US07514458B2

Reaction notes

Loading…