1-Methylcyclopropanecarboxamide → 3-Methyl-2-(1-methyl-cyclopropyl)-3h-imidazole-4-carbaldehyde

HRID 2109237Notes

Reaction equation

[CH3:1][C:2]1([C:5]([NH2:7])=O)[CH2:4][CH2:3]1.C1([C:11]2[N:15](C)[C:14]([CH:17]=[O:18])=[CH:13]N=2)CC1>>[CH3:11][N:15]1[C:14]([CH:17]=[O:18])=[CH:13][N:7]=[C:5]1[C:2]1([CH3:1])[CH2:4][CH2:3]1

Participants

Reactant 2

HCID 130029361-Methylcyclopropanecarboxamide

HCID 210972742-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde

Product 1

HCID 210973113-Methyl-2-(1-methyl-cyclopropyl)-3h-imidazole-4-carbaldehyde

Procedure

3-Methyl-2-(1-methyl-cyclopropyl)-3H-imidazole-4-carbaldehyde was prepared from 1-methyl-cyclopropyl carboxamide in the same manner as 2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde (Example 46).

Sources & evidence

ORD record: ord-fbdf7500c5d84756bf13ebcf2fcaa27d
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07514458B2

Reaction notes

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