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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109242Generated: October 26, 2026

Ethyl Acetoacetate → 1-tert-Butyl-5-methyl-1H-pyrazole-4-carbaldehyde

https://huagongshe.com/reaction/2109242

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetoacetateHCID 8868—
Reactanttert-Butylhydrazine monohydrochlorideHCID 81889—
Reactant5-cyclopropyl-1-(propan-2-yl)-1H-pyrazole-4-carbaldehydeHCID 19620135—
Product1-tert-Butyl-5-methyl-1H-pyrazole-4-carbaldehydeHCID 21097249—

Reaction Steps

1-tert-Butyl-5-methyl-1H-pyrazole-4-carbaldehyde was prepared with ethyl acetoacetate and tert-butyl hydrazine hydrochloride in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carbaldehyde (Example 49).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-8f7190d04e124722b1ed4b50ca4c36c8
Source noteuspto-grants-2009_04