Methyl iodide → 1,1-Dimethyl-4-oxopiperidin-1-ium iodide

Participants

Reaction Conditions

Reaction Steps

To 45.0 g (398 mmol) of 1-methyl-piperid-4-one in 500 mL of acetone was added dropwise 60.0 g (423 mmol) of MeI over 1 h. The mixture was stirred for 3 h, cooled to 0° C., and filtered. The solids were washed with cold acetone, and dried to provide 1,1-dimethyl-4-oxo-piperidinium iodide as a pale yellow solid (95.3 g).

Provenance & Evidence