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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109273Generated: October 31, 2026

Ethyl Acetoacetate → 1-(1-tert-Butyl-piperidin-4-yl)-5-methyl-1H-pyrazole-4-carbaldehyde

https://huagongshe.com/reaction/2109273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetoacetateHCID 8868—
Reactant5-cyclopropyl-1-(propan-2-yl)-1H-pyrazole-4-carbaldehydeHCID 19620135—
Reactant(1-Tert-butyl-piperidin-4-yl)-hydrazineHCID 21097250—
Product1-(1-tert-Butyl-piperidin-4-yl)-5-methyl-1H-pyrazole-4-carbaldehydeHCID 21097226—

Reaction Steps

1-(1-tert-Butyl-piperidin-4-yl)-5-methyl-1H-pyrazole-4-carbaldehyde was prepared from ethyl acetoacetate and (1-tert-butyl-piperidin-4-yl)-hydrazine in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carbaldehyde (Example 49).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-3ea03a5e6a79485594da0f15b01ef6c9
Source noteuspto-grants-2009_04