HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → 1-Benzyl-4-hydrazinylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | 1-Benzyl-4-piperidone | HCID 19220 | — |
| Reactant | 1-Benzyl-4-hydrazinylpiperidine | HCID 416192 | — |
| Reactant | 4-Hydrazinyl-1-methylpiperidine | HCID 10920535 | — |
| Reactant | 5-cyclopropyl-1-(propan-2-yl)-1H-pyrazole-4-carbaldehyde | HCID 19620135 | — |
| Product | 1-Benzyl-4-hydrazinylpiperidine | HCID 416192 | — |
| Product | 1-(1-Benzyl-piperidin-4-yl)-5-methyl-1H-pyrazole-4-carbaldehyde | HCID 21097225 | — |
Reaction Steps
1-(1-Benzyl-piperidin-4-yl)-5-methyl-1H-pyrazole-4-carbaldehyde was prepared from ethyl acetoacetate and (1-benzyl-piperidin-4-yl)-hydrazine in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carbaldehyde (Example 49). (1-Benzyl-piperidin-4-yl)-hydrazine was prepared from 1-benzyl-piperidin-4-one in the same manner as (1-methyl-piperidin-4-yl)-hydrazine (Example 92).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514458B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-88e3dcf0948c4fbc9e8a474c3810e9fd |
| Source note | uspto-grants-2009_04 |