HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate → N-Boc-4-(2-Cyclopropyl-4-ethoxycarbonyl-2H-pyrazol-3-yl)-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate | HCID 6618868 | — |
| Reactant | N-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-3-[4-(5-cyclopropyl-1-isopropyl-1H-pyrazol-4-yl)-[1,2,3]triazol-1-yl]-4-methyl-benzamide | HCID 21097161 | — |
| Reactant | Cyclopropylhydrazine oxalate | HCID 67509750 | — |
| Product | N-Boc-4-(2-Cyclopropyl-4-ethoxycarbonyl-2H-pyrazol-3-yl)-piperidine | HCID 21097372 | — |
Reaction Steps
N-Boc-4-(2-Cyclopropyl-4-ethoxycarbonyl-2H-pyrazol-3-yl)-piperidine was prepared from N-Boc-4-(2-ethoxycarbonyl-acetyl)-piperidine and cyclopropyl hydrazine oxalate in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carboxylic acid ethyl ester (Example 49).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514458B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-8e852888f340441d882d5b2604818512 |
| Source note | uspto-grants-2009_04 |