HRID2109304

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21024303

未命名化合物

结构：CCc1c(-c2cn(-c3cc(C(=O)OC)ccc3C)cn2)cnn1-c1ccccc1

HCID58861445

未命名化合物

PRODUCTS

生成物

结构：CCc1c(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)cnc4C)ccc3C)cn2)cnn1-c1ccccc1

HCID21097107

未命名化合物

PROCEDURE

实验过程

Example 152 was prepared from 5-tert-butyl-2-methyl-pyridin-3-ylamine (see U.S. provisional application 60/567,693) and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 519 [C32H34N6O+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d863d951d0de4586bcc829ec1d1d5d16
来源数据集: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07514458B2
来源说明: uspto-grants-2009_04

反应 SMILES

[C:1]([C:5]1[CH:6]=[C:7]([NH2:12])[C:8]([CH3:11])=[N:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C[O:14][C:15](=O)[C:16]1[CH:21]=[CH:20][C:19]([CH3:22])=[C:18]([N:23]2[CH:27]=[C:26]([C:28]3[CH:29]=[N:30][N:31]([C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)[C:32]=3[CH2:33][CH3:34])[N:25]=[CH:24]2)[CH:17]=1>>[C:1]([C:5]1[CH:6]=[C:7]([NH:12][C:15](=[O:14])[C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[C:18]([N:23]3[CH:27]=[C:26]([C:28]4[CH:29]=[N:30][N:31]([C:35]5[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=5)[C:32]=4[CH2:33][CH3:34])[N:25]=[CH:24]3)[CH:17]=2)[C:8]([CH3:11])=[N:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2]