5-Tert-butyl-2-methanesulfinyl-phenylamine → N-(5-tert-Butyl-2-methanesulfinyl-phenyl)-3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzamide

HRID 2109308ノート

反応式

HRID 2109308 の反応式
[C:1]([C:5]1[CH:6]=[CH:7][C:8]([S:12]([CH3:14])=[O:13])=[C:9]([NH2:11])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C[O:16][C:17](=O)[C:18]1[CH:23]=[CH:22][C:21]([CH3:24])=[C:20]([N:25]2[CH:29]=[C:28]([C:30]3[CH:31]=[N:32][N:33]([C:37]4[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=4)[C:34]=3[CH2:35][CH3:36])[N:27]=[CH:26]2)[CH:19]=1>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([S:12]([CH3:14])=[O:13])=[C:9]([NH:11][C:17](=[O:16])[C:18]2[CH:23]=[CH:22][C:21]([CH3:24])=[C:20]([N:25]3[CH:29]=[C:28]([C:30]4[CH:31]=[N:32][N:33]([C:37]5[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=5)[C:34]=4[CH2:35][CH3:36])[N:27]=[CH:26]3)[CH:19]=2)[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

参加物

3

反応物 2

HCID 210973535-Tert-butyl-2-methanesulfinyl-phenylamineHCID 588614453-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester

生成物 1

HCID 21097103N-(5-tert-Butyl-2-methanesulfinyl-phenyl)-3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzamide

実験手順

Example 156 was prepared from 5-tert-butyl-2-methanesulfinyl-phenylamine and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 566 [C33H35N5O2S+H]+.

出典と根拠

ORDレコード
ord-a647795f77694684a94454da64fd493b
出典データセット
uspto-grants-2009_04
特許番号
US07514458B2

反応ノート

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