HRID2109310

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10214710

未命名化合物

结构：CCc1c(-c2cn(-c3cc(C(=O)OC)ccc3C)cn2)cnn1-c1ccccc1

HCID58861445

未命名化合物

PRODUCTS

生成物

结构：CCc1c(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)ccc3C)cn2)cnn1-c1ccccc1

HCID21097165

未命名化合物

PROCEDURE

实验过程

Example 158 was prepared from N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 627 [C34H38N6O4S+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e8b7e22bcce149f3aa0c8915be62f07e
来源数据集: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07514458B2
来源说明: uspto-grants-2009_04

反应 SMILES

[NH2:1][C:2]1[C:3]([O:17][CH3:18])=[C:4]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[CH:5]=[C:6]([C:8]([CH3:11])([CH3:10])[CH3:9])[CH:7]=1.C[O:20][C:21](=O)[C:22]1[CH:27]=[CH:26][C:25]([CH3:28])=[C:24]([N:29]2[CH:33]=[C:32]([C:34]3[CH:35]=[N:36][N:37]([C:41]4[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=4)[C:38]=3[CH2:39][CH3:40])[N:31]=[CH:30]2)[CH:23]=1>>[C:8]([C:6]1[CH:5]=[C:4]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[C:3]([O:17][CH3:18])=[C:2]([NH:1][C:21](=[O:20])[C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[C:24]([N:29]3[CH:33]=[C:32]([C:34]4[CH:35]=[N:36][N:37]([C:41]5[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=5)[C:38]=4[CH2:39][CH3:40])[N:31]=[CH:30]3)[CH:23]=2)[CH:7]=1)([CH3:10])([CH3:11])[CH3:9]