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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109311Generated: November 2, 2026

N-(3-amino-2-methoxy-5-trifluoromethyl-phenyl)-methanesulfonamide → 3-[4-(5-Ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-N-(3-methanesulfonylamino-2-methoxy-5-trifluoromethyl-phenyl)-4-methyl-benzamide

https://huagongshe.com/reaction/2109311

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-amino-2-methoxy-5-trifluoromethyl-phenyl)-methanesulfonamideHCID 22506980—
Reactant3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl esterHCID 58861445—
Product3-[4-(5-Ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-N-(3-methanesulfonylamino-2-methoxy-5-trifluoromethyl-phenyl)-4-methyl-benzamideHCID 21097094—

Reaction Steps

Example 159 was prepared from N-(3-amino-2-methoxy-5-trifluoromethyl-phenyl)-methanesulfonamide and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 639 [C31H29F3N6O4S+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-7253c531d8f048ee8c8a8e5cd3b68066
Source noteuspto-grants-2009_04