Bismuth trichloride → HCID 13174771, compound

Participants

Reaction Conditions

Reaction Steps

A 82.6 g quantity of Compound 1 was dissolved in 300 mL of dichloromethane. To the solution was added 115 mL of 20% aqueous solution of ammonium chloride and 36 mL of methanol with stirring. After adding 1.6 g of bismuth chloride, 10 g of aluminum powder was gradually added to the mixture while maintaining at 20 to 30° C. The mixture was reacted for 5 hours while maintaining at 20 to 30° C. After adding 120 mL of water, insoluble metalresidue was filtered and an orgaic layer was separated. The organic layer was washed with 120 mL of 5% aqueous solution of sodium chloride. The organic layer was concentrated to give Compound 2.

Provenance & Evidence