Methanol → HCID 13174771, compound

Participants

Reaction Steps

A 42 g quantity of Compound 1 was dissolved in 300 mL of dichloromethane. To the solution was added 0.9 g of bismuth sulfate and 57 mL of 20% aqueous solution of sodium chloride with stirring. To the mixture were added 10 g of iron powder and 17 mL of methanol with stirring at room temperature for 9 hours. Further, the mixture was stirred for 10 hours with adding 0.8 g of bismuth sulfate, and stirred at 35° C. for 2 hours. After completion of reaction, 100 mL of water was added and an orgaic layer was separated. The organic layer was washed with 100 mL of 5% aqueous solution of sodium chloride. The organic layer was concentrated to give Compound 2.

Provenance & Evidence