Dichloromethane → HCID 23062507, compound

HRID 2109381Notes

Reaction equation

HRID 2109381 reaction equation
[Br:1]Br.ClCCl.[C:6]1([C:12]2[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:15][O:14][C:13]=2[C:23]([O:25][CH3:26])=[O:24])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>C(Cl)(Cl)Cl>[Br:1][C:15]1[O:14][C:13]([C:23]([O:25][CH3:26])=[O:24])=[C:12]([C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:16]=1[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 24408BromineHCID 162667Methyl 3,4-diphenyl-2-furoate

Product 1

HCID 23062507HCID 23062507, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Bromine (0.18 ml) was added to a dichloromethane (10 ml) solution of methyl 3,4-diphenyl-2-furancarboxylate (1.00 g) at 0° C., and stirred at this temperature for 4 hours. The reaction solution was diluted with chloroform, and successively washed with water, saturated aqueous sodium hydrogencarbonate solution, and saturated brine. The organic layer was dried over MgSO4, and the solvent was evaporated under reduced pressure, thereby giving 1.28 g of methyl 5-bromo-3,4-diphenyl-2-furancarboxylate.

Workup

  1. washsuccessively washed with water, saturated aqueous sodium hydrogencarbonate solution, and saturated brine
  2. dry with materialThe organic layer was dried over MgSO4
  3. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-e4e37001c0ea444b9fe91427b76105eb
Source dataset
uspto-grants-2009_04
Patent number
US07514452B2

Reaction notes

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